An efficient multiple imputation algorithm for control-based and delta-adjusted pattern mixture models using SAS

12 Oct 2016 Tang Yongqiang

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can be easily implemented in standard statistical software packages such as SAS PROC MI... (read more)

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  • METHODOLOGY